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One way to test the performance of a registration algorithm is to take some image data and then apply known artificial warps to it [,]. This means that the ground-truth correspondence is known. This approach can be used to compare the performance of different NRR algorithms, but, since it relies on the creation of artificial test data, cannot be applied in-line. Also, the validity of the approach depends on the ability to construct artificial deformations which mimic the variability found in real images of a given type, which is difficult to guarantee.
