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Effect of Noise

The validation experiments were repeated and sensitivity analysis reported above with added image noise. Although the absolute values of the model-based measures were shifted upwards, as would be expected, there were no changes in the relative values, nor any systematic or statistically significant changes in sensitivity, even for 10% added noise. Figure  shows that as the degree of noise increased, Specificity is still able to detect significant differences in terms of the level of misregistration.