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Concurrent Advancements

The work of Marsland, Twining and Taylor [] went a step ahead and investigated a full 2-D model^B.3. However, it concentrated on just a simple contour (defined by 12 control points) of the skull shape as pictured from an overhead perspective. Figure shows that warps can have an effect on the whole shape, but still lack some control over local structures such as the ventricles. Varying scale can solve problems like this and make the global non-rigid registration approach very robust. While this work produced elegant results, it did not explore many varying options as in the case of Smith.

Figure: Brain image warping. Points on the skull depict knot-points for the splines.